1.3M XNAS Volume
XNAS 20 Mar, 2025 3:10 PM (EDT)
| Client Name | Client Category | Action | Reported to Exchange | Quantity | Post Transaction Holding | Traded % | Avg. Price | Value | Security Type |
|---|---|---|---|---|---|---|---|---|---|
| Siobhan Fogarty | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 13,500 | 13,500 | - | - | Stock Option | |
| Siobhan Fogarty | Chief Technology Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2025 | 13,500 | 13,500 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 123,958 | 123,958 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 05 Feb 2025 | 1 | 0 (0%) | 0% | 0 | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Other type of transaction at price $ 3.60 per share. | 05 Feb 2025 | 5 | 5 (0%) | 0% | 3.6 | 18 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 123,958 | 123,958 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 29,017 | 29,017 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 29,017 | 29,017 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Other type of transaction at price $ 0.00 per share. | 05 Feb 2025 | 1 | 0 (0%) | 0% | 0 | Common Stock, $0.001 par value | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 29,291 | 29,291 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 29,291 | 29,291 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 25,792 | 25,792 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Feb 2025 | 25,792 | 25,792 | - | - | Stock Option | |
| Margaret Smith Bell | Director | Other type of transaction at price $ 0.00 per share. | 05 Feb 2025 | 1 | 0 (0%) | 0% | 0 | Common Stock, par value $0.001 | |
| Adeoye Y. Olukotun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| David L. Grange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| Richard H. Bagger | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| Margaret Smith Bell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| Carolyn E. Taylor | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| Richard Newcomb Stillwell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 May 2024 | 104,621 | 104,621 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 317,000 | 317,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 358,000 | 358,000 | - | - | Stock Option | |
| Lederman Seth | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 1,309,911 | 1,309,911 | - | - | Stock Option | |
| Jessica Morris Edgar | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 317,000 | 317,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 282,000 | 282,000 | - | - | Stock Option | |
| Lederman Seth | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 235,320 | 235,320 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 1,903,680 | 1,903,680 | - | - | Stock Option | |
| M. Sullivan Gregory | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 358,000 | 358,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 282,000 | 282,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 235,320 | 235,320 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 1,309,911 | 1,309,911 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 Feb 2024 | 1,903,680 | 1,903,680 | - | - | Stock Option | |
| Adeoye Y. Olukotun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| David L. Grange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| Richard H. Bagger | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| Margaret Smith Bell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| Carolyn E. Taylor | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| Richard Newcomb Stillwell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 08 May 2023 | 60,000 | 60,000 | - | - | Stock Option | |
| Richard Newcomb Stillwell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Mar 2023 | 83,000 | 83,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 700,000 | 700,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 700,000 | 700,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 220,000 | 220,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 220,000 | 220,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 207,500 | 207,500 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 207,500 | 207,500 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 200,000 | 200,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2023 | 200,000 | 200,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 1.71 per share. | 29 Jun 2022 | 20,000 | 24,235 (0%) | 0% | 1.7 | 34,200 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.24 per share. | 25 Mar 2022 | 100,000 | 112,177 (0%) | 0% | 0.2 | 24,500 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 5,000,000 | 5,000,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 5,000,000 | 5,000,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 5,000,000 | 5,000,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 5,000,000 | 5,000,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,250,000 | 1,250,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,250,000 | 1,250,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,250,000 | 1,250,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,250,000 | 1,250,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,100,000 | 1,100,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,100,000 | 1,100,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,100,000 | 1,100,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 1,100,000 | 1,100,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 900,000 | 900,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 900,000 | 900,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 900,000 | 900,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 15 Feb 2022 | 900,000 | 900,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.61 per share. | 28 Sep 2021 | 12,000 | 12,177 (0%) | 0% | 0.6 | 7,320 | Common Stock, $0.001 par value |
| Carolyn E. Taylor | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Jul 2021 | 237,437 | 237,437 | - | - | Stock Option | |
| Daniel Goodman | Director | Purchase of securities on an exchange or from another person at price $ 1.12 per share. | 25 May 2021 | 5,000 | 5,001 (0%) | 0% | 1.1 | 5,600 | Common Stock |
| Adeoye Y. Olukotun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2021 | 270,882 | 270,882 | - | - | Stock Option | |
| David L. Grange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2021 | 270,882 | 270,882 | - | - | Stock Option | |
| Richard H. Bagger | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2021 | 270,882 | 270,882 | - | - | Stock Option | |
| Margaret Smith Bell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2021 | 270,882 | 270,882 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2021 | 270,882 | 270,882 | - | - | Stock Option | |
| Daniel Goodman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 10 May 2021 | 270,882 | 270,882 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 1.32 per share. | 24 Mar 2021 | 16,733 | 135,000 (0%) | 0% | 1.3 | 22,088 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 3,000,000 | 3,000,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 3,000,000 | 3,000,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 750,000 | 750,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 750,000 | 750,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.51 per share. | 23 Feb 2021 | 41,322 | 62,727 (0%) | 0% | 0.5 | 21,074 | Common Stock, $0.001 par value |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 540,000 | 540,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 540,000 | 540,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 540,000 | 540,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 23 Feb 2021 | 540,000 | 540,000 | - | - | Stock Option | |
| James Treco | Director | Purchase of securities on an exchange or from another person at price $ 0.89 per share. | 31 Aug 2020 | 5,500 | 10,000 (0%) | 0% | 0.9 | 4,895 | Common Stock, par value $0.001 |
| Margaret Smith Bell | Director | Purchase of securities on an exchange or from another person at price $ 0.93 per share. | 20 Aug 2020 | 5,391 | 5,391 (0%) | 0% | 0.9 | 4,997 | Common Stock, par value $0.001 |
| Gregory M. Sullivan | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 1.03 per share. | 17 Aug 2020 | 20,000 | 21,405 (0%) | 0% | 1.0 | 20,600 | Common Stock, par value $0.001 |
| James Treco | Director | Purchase of securities on an exchange or from another person at price $ 1.06 per share. | 14 Aug 2020 | 4,500 | 4,500 (0%) | 0% | 1.1 | 4,770 | Common Stock, par value $0.001 |
| Adeoye Y. Olukotun | Director | Purchase of securities on an exchange or from another person at price $ 0.94 per share. | 13 Aug 2020 | 5,350 | 5,350 (0%) | 0% | 0.9 | 5,029 | Common Stock, par value $0.001 |
| Richard H. Bagger | Director | Purchase of securities on an exchange or from another person at price $ 0.91 per share. | 13 Aug 2020 | 10,000 | 10,000 (0%) | 0% | 0.9 | 9,100 | Common Stock, par value $0.001 |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.91 per share. | 13 Aug 2020 | 60,000 | 83,267 (0%) | 0% | 0.9 | 54,600 | Common Stock, $0.001 par value |
| Richard H. Bagger | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Jun 2020 | 68,750 | 68,750 | - | - | Stock Option | |
| Adeoye Y. Olukotun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 75,000 | 75,000 | - | - | Stock Option | |
| David L. Grange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 75,000 | 75,000 | - | - | Stock Option | |
| John B. Rhodes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 75,000 | 75,000 | - | - | Stock Option | |
| Seth Lederman | Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 2,000,000 | 2,000,000 | - | - | Stock Option | |
| Seth Lederman | Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 2,000,000 | 2,000,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 500,000 | 500,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 500,000 | 500,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 360,000 | 360,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 360,000 | 360,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 360,000 | 360,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 360,000 | 360,000 | - | - | Stock Option | |
| Margaret Smith Bell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 75,000 | 75,000 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 112,500 | 112,500 | - | - | Stock Option | |
| Daniel Goodman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 04 May 2020 | 75,000 | 75,000 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 16 Mar 2020 | 6,000 | 6,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 120,000 | 120,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 120,000 | 120,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 39,000 | 39,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 39,000 | 39,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 24,000 | 24,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 24,000 | 24,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 24,000 | 24,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2020 | 24,000 | 24,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 11.82 per share. | 31 Dec 2019 | 1,142 | 1,405 (0%) | 0% | 11.8 | 13,498 | Common Stock, par value $0.001 |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 17.85 per share. | 31 Dec 2019 | 59 | 1,405 (0%) | 0% | 17.8 | 1,053 | Common Stock, par value $0.001 |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 11.82 per share. | 31 Dec 2019 | 815 | 904 (0%) | 0% | 11.8 | 9,633 | Common Stock, par value $0.001 |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 17.85 per share. | 31 Dec 2019 | 59 | 904 (0%) | 0% | 17.8 | 1,053 | Common Stock, par value $0.001 |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 1.16 per share. | 03 Dec 2019 | 20,000 | 23,267 (0%) | 0% | 1.2 | 23,180 | Common Stock, $0.001 par value |
| Adeoye Y. Olukotun | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| David L. Grange | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| John B. Rhodes | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 45,000 | 45,000 | - | - | Stock Option | |
| Patrick P. Grace | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 129,758 | 129,758 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 129,757 | 129,757 | - | - | Stock Option | |
| Donald W. Landry | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 43,252 | 43,252 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 43,253 | 43,253 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 28,835 | 28,835 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 28,835 | 28,835 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 28,835 | 28,835 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 28,835 | 28,835 | - | - | Stock Option | |
| Margaret Smith Bell | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Daniel Goodman | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 06 May 2019 | 30,000 | 30,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.49 per share. | 29 Mar 2019 | 5,000 | 32,670 (0%) | 0% | 2.5 | 12,440 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.38 per share. | 26 Mar 2019 | 25,000 | 27,670 (0%) | 0% | 2.4 | 59,375 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 23,265 | 23,265 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 23,265 | 23,265 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 7,755 | 7,755 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 7,755 | 7,755 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 5,170 | 5,170 | - | - | Common Stock | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 5,170 | 5,170 | - | - | Common Stock | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 5,170 | 5,170 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 26 Feb 2019 | 5,170 | 5,170 | - | - | Stock Option | |
| James Treco | Director | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 14 Feb 2019 | 10,000 | 10,000 | - | - | Stock Option | |
| Adeoye Y. Olukotun | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 05 Sep 2018 | 15,000 | 15,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.64 per share. | 29 Jun 2018 | 500 | 17,666 (0%) | 0% | 4.6 | 2,320 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.58 per share. | 28 Jun 2018 | 500 | 17,166 (0%) | 0% | 4.6 | 2,290 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.55 per share. | 27 Jun 2018 | 500 | 16,666 (0%) | 0% | 4.6 | 2,275 | Common Stock, $0.001 par value |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 4.48 per share. | 25 Jun 2018 | 16,500 | 50,000 (0%) | 0% | 4.5 | 73,920 | Common Stock, $0.001 par value |
| Gregory M. Sullivan | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 3.96 per share. | 14 Jun 2018 | 10,000 | 20,482 (0%) | 0% | 4.0 | 39,650 | Common Stock, $0.001 par value |
| Jessica Edgar Morris | Chief Operating Officer | Purchase of securities on an exchange or from another person at price $ 4.19 per share. | 14 Jun 2018 | 300 | 1,638 (0%) | 0% | 4.2 | 1,257 | Common Stock, $0.001 par value |
| Bradley Saenger | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 4.10 per share. | 14 Jun 2018 | 300 | 3,079 (0%) | 0% | 4.1 | 1,230 | Common Stock, $0.001 par value |
| David L. Grange | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 30,000 | 30,000 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.37 per share. | 12 Jun 2018 | 1,000 | 16,166 (0%) | 0% | 4.4 | 4,370 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.37 per share. | 12 Jun 2018 | 2,000 | 20,463 (0%) | 0% | 4.4 | 8,740 | Common Stock, $0.001 par value |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| Charles E. Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| Margaret Smith Bell | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Jun 2018 | 20,000 | 20,000 | - | - | Stock Option | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 3.33 per share. | 01 Jun 2018 | 7,500 | 23,470 (0%) | 0% | 3.3 | 24,975 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 3.17 per share. | 25 May 2018 | 4,000 | 26,700 (0%) | 0% | 3.2 | 12,680 | Common Stock, $0.001 par value |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 27 Feb 2018 | 750 | 12,580 (0%) | 0% | 0 | Common Stock, $0.001 par value | |
| David L. Grange | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 7,000 | 7,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 156,601 | 156,601 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 156,601 | 156,601 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 58,725 | 58,725 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 58,726 | 58,726 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 39,150 | 39,150 | - | - | Stock Option | |
| Jessica Edgar Morris | Chief Operating Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 39,150 | 39,150 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 39,150 | 39,150 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 13 Feb 2018 | 39,150 | 39,150 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 3.61 per share. | 26 Dec 2017 | 5,300 | 22,700 (0%) | 0% | 3.6 | 19,133 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 3.55 per share. | 14 Dec 2017 | 5,000 | 53,500 (0%) | 0% | 3.6 | 17,750 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 3.46 per share. | 14 Dec 2017 | 5,000 | 23,500 (0%) | 0% | 3.5 | 17,300 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 3.44 per share. | 14 Dec 2017 | 8,965 | 28,500 (0%) | 0% | 3.4 | 30,840 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 3.58 per share. | 14 Dec 2017 | 1,967 | 55,467 (0%) | 0% | 3.6 | 7,042 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 3.51 per share. | 14 Dec 2017 | 6,035 | 37,465 (0%) | 0% | 3.5 | 21,183 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 3.57 per share. | 14 Dec 2017 | 10,000 | 43,500 (0%) | 0% | 3.6 | 35,700 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 3.00 per share. | 16 Aug 2017 | 15,000 | 50,000 (0%) | 0% | 3.0 | 45,068 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 2.99 per share. | 16 Aug 2017 | 5,000 | 35,000 (0%) | 0% | 3.0 | 14,950 | Common Stock, $0.001 par value |
| Ernest Mario | None | Sale of securities on an exchange or to another person at price $ 4.28 per share. | 30 Jun 2017 | 6,105 | 5,895 (0%) | 0% | 4.3 | 26,117 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.33 per share. | 30 Jun 2017 | 5,000 | 30,000 (0%) | 0% | 4.3 | 21,640 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.40 per share. | 26 Jun 2017 | 5,000 | 25,000 (0%) | 0% | 4.4 | 22,000 | Common Stock, $0.001 par value |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 30,000 | 30,000 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 20,000 | 20,000 | - | - | Stock Option | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 20,000 | 20,000 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 20,000 | 20,000 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 20,000 | 20,000 | - | - | Stock Option | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 20,000 | 20,000 | - | - | Stock Option | |
| Charles E. Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 20 Jun 2017 | 20,000 | 20,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 4.22 per share. | 19 Jun 2017 | 20,000 | 20,000 (0%) | 0% | 4.2 | 84,400 | Common Stock, $0.001 par value |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2017 | 160,000 | 160,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2017 | 160,000 | 160,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2017 | 75,000 | 75,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2017 | 75,000 | 75,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2017 | 47,500 | 47,500 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 01 Mar 2017 | 47,500 | 47,500 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2016 | 3,296 | 79,111 | - | - | Common Stock | |
| Gregory M. Sullivan | Chief Medical Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2016 | 3,296 | 46,481 | - | - | Common Stock | |
| Bradley Saenger | Chief Financial Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2016 | 3,296 | 9,335 | - | - | Common Stock | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Nov 2016 | 120,000 | 120,000 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Nov 2016 | 98,000 | 133,000 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Oct 2016 | 100,000 | 100,000 | - | - | Common Stock Purchase Warrant | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Oct 2016 | 100,000 | 630,724 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Oct 2016 | 25,000 | 25,000 | - | - | Common Stock Purchase Warrant | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Oct 2016 | 25,000 | 137,196 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Oct 2016 | 10,000 | 10,000 | - | - | Common Stock Purchase Warrant | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 Oct 2016 | 10,000 | 90,815 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 13 Sep 2016 | 100,000 | 530,724 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 Jun 2016 | 20,000 | 20,000 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Jun 2016 | 50,000 | 430,724 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Jun 2016 | 25,000 | 112,196 | - | - | Common Stock, $0.001 par value | |
| Samuel R. Saks | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Jun 2016 | 12,500 | 51,050 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Jun 2016 | 25,000 | 31,000 | - | - | Common Stock, $0.001 par value | |
| Bruce Daugherty | See remarks | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Jun 2016 | 100,000 | 100,000 | - | - | Common Stock, $0.001 par value | |
| Bradley Saenger | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 Jun 2016 | 2,000 | 6,039 | - | - | Common Stock, $0.001 par value | |
| Gregory M. Sullivan | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 03 Jun 2016 | 20,000 | 43,185 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 11,250 | 11,250 | - | - | Restricted Stock Unit | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Charles E. Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 20,000 | 20,000 | - | - | Stock Option | |
| Bradley Saenger | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 27 May 2016 | 60,000 | 60,000 | - | - | Stock Option | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 May 2016 | 31,042 | 380,724 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 May 2016 | 8,210 | 349,682 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 Mar 2016 | 8,000 | 80,815 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 16 Mar 2016 | 75,000 | 341,472 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Ernest Mario | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Ernest Mario | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 0 | - | - | Restricted Stock Units | |
| Ernest Mario | None | Gift of securities by or to the insider at price $ 0.00 per share. | 25 Feb 2016 | 10,000 | 0 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Gift of securities by or to the insider at price $ 0.00 per share. | 25 Feb 2016 | 10,000 | 33,500 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 64,572 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 63,822 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 26,648 | - | - | Common Stock, $0.001 par value | |
| Patrick P. Grace | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Patrick P. Grace | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Patrick P. Grace | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 0 | - | - | Restricted Stock Units | |
| Patrick P. Grace | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 2,755 | - | - | Common Stock, $0.001 par value | |
| Patrick P. Grace | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 2,005 | - | - | Common Stock, $0.001 par value | |
| Patrick P. Grace | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 1,255 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 1,125 | 0 | - | - | Restricted Stock Units | |
| John B. Rhodes | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 1,125 | 0 | - | - | Restricted Stock Units | |
| John B. Rhodes | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 0 | - | - | Restricted Stock Units | |
| John B. Rhodes | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 1,125 | 15,970 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 1,125 | 14,845 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 8,720 | - | - | Common Stock, $0.001 par value | |
| Samuel R. Saks | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Samuel R. Saks | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Samuel R. Saks | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 650 | 0 | - | - | Restricted Stock Units | |
| Samuel R. Saks | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 6,605 | - | - | Common Stock, $0.001 par value | |
| Samuel R. Saks | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 5,855 | - | - | Common Stock, $0.001 par value | |
| Samuel R. Saks | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 3,855 | - | - | Common Stock, $0.001 par value | |
| Donald W. Landry | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Donald W. Landry | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Donald W. Landry | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 0 | - | - | Restricted Stock Units | |
| Donald W. Landry | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 9,210 | - | - | Common Stock, $0.001 par value | |
| Donald W. Landry | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 8,460 | - | - | Common Stock, $0.001 par value | |
| Donald W. Landry | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 7,710 | - | - | Common Stock, $0.001 par value | |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 0 | - | - | Restricted Stock Units | |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 0 | - | - | Restricted Stock Units | |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 3,283 | - | - | Common Stock, $0.001 par value | |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 750 | 2,533 | - | - | Common Stock, $0.001 par value | |
| Charles E. Mather | None | Exercise or conversion of derivative security received from the company (such as an option) at price $ 0.00 per share. | 25 Feb 2016 | 600 | 1,783 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 11,250 | 0 | - | - | Restricted Stock Unit | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 110,000 | 110,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 110,000 | 110,000 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Charles E. Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 7,500 | 7,500 | - | - | Restricted Stock Unit | |
| Bruce Daugherty | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 30,000 | 30,000 | - | - | Stock Option | |
| Bruce Daugherty | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 30,000 | 30,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 30,000 | 30,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 30,000 | 30,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Acting Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 30,000 | 30,000 | - | - | Stock Option | |
| Jessica Edgar Morris | Acting Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 09 Feb 2016 | 30,000 | 30,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2015 | 1,741 | 72,815 | - | - | Common Stock | |
| Bruce Daugherty | See Remarks | Other type of transaction at price $ 0.00 per share. | 31 Dec 2015 | 3,532 | 63,049 | - | - | Common Stock | |
| Bruce Daugherty | See Remarks | Other type of transaction at price $ 0.00 per share. | 31 Dec 2015 | 2,728 | 65,777 | - | - | Common Stock | |
| Gregory M. Sullivan | Chief Medical Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2015 | 3,532 | 20,457 | - | - | Common Stock | |
| Gregory M. Sullivan | Chief Medical Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2015 | 2,728 | 23,185 | - | - | Common Stock | |
| Jessica Edgar Morris | Acting Chief Financial Officer | Other type of transaction at price $ 0.00 per share. | 31 Dec 2015 | 909 | 3,580 | - | - | Common Stock | |
| Gregory M. Sullivan | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 30 Sep 2015 | 5,000 | 20,457 | - | - | Common Stock, $0.001 par value | |
| Leland Gershell | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 28 Sep 2015 | 400 | 19,260 | - | - | Common Stock, $0.001 par value | |
| Gregory M. Sullivan | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 28 Sep 2015 | 4,694 | 15,457 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 Sep 2015 | 6,000 | 71,074 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 26 Aug 2015 | 10,000 | 260,472 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 25 Aug 2015 | 1,468 | 250,472 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 Aug 2015 | 2,532 | 249,004 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 Aug 2015 | 6,000 | 246,472 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Aug 2015 | 15,000 | 240,472 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jul 2015 | 25,000 | 225,472 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jul 2015 | 6,000 | 81,196 | - | - | Common Stock, $0.001 par value | |
| Samuel R. Saks | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jul 2015 | 10,000 | 32,550 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jul 2015 | 6,000 | 6,000 | - | - | Common Stock, $0.001 par value | |
| Leland Gershell | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 17 Jul 2015 | 1,000 | 18,860 | - | - | Common Stock, $0.001 par value | |
| Gregory M. Sullivan | Chief Medical Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 11 Jun 2015 | 4,500 | 7,231 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 16 Mar 2015 | 1,000 | 64,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 16 Mar 2015 | 1,000 | 65,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Mar 2015 | 1,000 | 62,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 12 Mar 2015 | 1,000 | 63,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Mar 2015 | 1,000 | 60,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Mar 2015 | 1,000 | 61,074 | - | - | Common Stock, $0.001 par value | |
| Charles Mather | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 10 Mar 2015 | 1,000 | 11,830 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Mar 2015 | 4,000 | 200,472 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Mar 2015 | 1,000 | 58,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Mar 2015 | 1,000 | 59,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Mar 2015 | 1,000 | 56,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Mar 2015 | 1,000 | 57,074 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 5,000 | 5,000 | - | - | Stock Option | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 5,000 | 5,000 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 7,500 | 7,500 | - | - | Stock Option | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 5,000 | 5,000 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 189,000 | 189,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 7,143 | 7,143 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 5,000 | 5,000 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 5,000 | 5,000 | - | - | Stock Option | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| Charles Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 5,000 | 5,000 | - | - | Stock Option | |
| Charles Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 6,000 | 6,000 | - | - | Restricted Stock Unit | |
| Leland Gershell | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 50,000 | 50,000 | - | - | Stock Option | |
| Bruce Daugherty | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 36,000 | 36,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 25 Feb 2015 | 26,500 | 26,500 | - | - | Stock Option | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Feb 2015 | 30,000 | 196,472 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Feb 2015 | 5,000 | 55,074 | - | - | Common Stock, $0.001 par value | |
| Leland Gershell | Chief Financial Officer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Feb 2015 | 5,000 | 17,860 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | 18 Dec 2014 | 30,000 | 0 | - | - | Series A common stock purchase warrant | ||
| Ernest Mario | None | 18 Dec 2014 | 30,000 | 166,472 | - | - | Common Stock, $0.001 par value | ||
| Leland Gershell | Chief Financial Officer | 17 Dec 2014 | 3,530 | 0 | - | - | Series A common stock purchase warrant | ||
| Leland Gershell | Chief Financial Officer | 17 Dec 2014 | 3,530 | 12,860 | - | - | Common Stock, $0.001 par value | ||
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Donald J. Kellerman | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 36,000 | 36,000 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 7,500 | 7,500 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 100,000 | 100,000 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Charles Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Leland Gershell | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 38,000 | 38,000 | - | - | Stock Option | |
| Bruce Daugherty | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 36,000 | 36,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 29 Oct 2014 | 26,500 | 26,500 | - | - | Stock Option | |
| Ernest Mario | None | 29 Sep 2014 | 10,000 | 136,472 | - | - | Common Stock, $0.001 par value | ||
| Ernest Mario | None | 29 Sep 2014 | 10,000 | 30,000 | - | - | Series A common stock purchase warrant | ||
| Ernest Mario | None | 26 Aug 2014 | 7,059 | 40,000 | - | - | Series A common stock purchase warrant | ||
| Ernest Mario | None | 26 Aug 2014 | 7,059 | 126,472 | - | - | Common Stock, $0.001 par value | ||
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Donald J. Kellerman | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 36,000 | 36,000 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 7,500 | 7,500 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 100,000 | 100,000 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 5,000 | 5,000 | - | - | Stock Option | |
| Charles Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 5,000 | 0 | - | - | Stock Option | |
| Leland Gershell | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 30,000 | 30,000 | - | - | Stock Option | |
| Bruce Daugherty | See Remarks | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 25,000 | 25,000 | - | - | Stock Option | |
| Gregory M. Sullivan | Chief Medical Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 17 Jun 2014 | 26,500 | 0 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 18 Mar 2014 | 25,000 | 29,167 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer | Other type of transaction at price $ 0.00 per share. | 18 Mar 2014 | 25,000 | 29,167 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 71,000 | 71,000 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| Charles Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 5,500 | 5,500 | - | - | Stock Option | |
| Leland Gershell | Chief Financial Officer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 32,000 | 32,000 | - | - | Stock Option | |
| Bruce Daugherty | SEE REMARKS | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 11 Feb 2014 | 26,000 | 26,000 | - | - | Stock Option | |
| Charles Mather | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 27 Sep 2013 | 1,000 | 10,830 | - | - | Common Stock | |
| Charles Mather | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 09 Sep 2013 | 600 | 9,830 | - | - | Common Stock | |
| Leland Gershell | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 06 Sep 2013 | 500 | 9,330 | - | - | Common Stock, $0.001 par value | |
| Charles Mather | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 04 Sep 2013 | 451 | 9,230 | - | - | Common Stock | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 47,059 | 119,713 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 47,059 | 47,059 | - | - | Series A common stock purchase warrant | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 11,765 | 75,196 | - | - | Common Stock, $0.001 par value | |
| John B. Rhodes | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 11,765 | 11,765 | - | - | Series A common stock purchase warrant | |
| Samuel R. Saks | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 5,883 | 5,883 | - | - | Series A common stock purchase warrant | |
| Samuel R. Saks | None | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 5,883 | 22,550 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 11,765 | 50,074 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, President and CEO | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 11,765 | 11,765 | - | - | Series A common stock purchase warrant | |
| Leland Gershell | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 3,530 | 3,530 | - | - | Series A common stock purchase warrant | |
| Leland Gershell | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 3,530 | 8,830 | - | - | Common Stock, $0.001 par value | |
| Bruce Daugherty | SEE REMARKS | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 47,059 | 47,059 | - | - | Series A common stock purchase warrant | |
| Bruce Daugherty | SEE REMARKS | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 14 Aug 2013 | 47,059 | 57,768 | - | - | Common Stock, $0.001 par value | |
| Bruce Daugherty | SEE REMARKS | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 31 May 2013 | 100 | 10,709 | - | - | Common Stock, $0.001 par value | |
| Bruce Daugherty | SEE REMARKS | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 29 May 2013 | 100 | 10,609 | - | - | Common Stock, $0.001 par value | |
| Bruce Daugherty | SEE REMARKS | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 24 May 2013 | 100 | 10,509 | - | - | Common Stock, $0.001 par value | |
| Leland Gershell | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 May 2013 | 150 | 5,300 | - | - | Common Stock, $0.001 par value | |
| Leland Gershell | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 23 May 2013 | 50 | 5,150 | - | - | Common Stock, $0.001 par value | |
| Bruce Daugherty | See Remarks | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 22 May 2013 | 200 | 10,409 | - | - | Common Stock, $0.001 par value | |
| Leland Gershell | CFO and Treasurer | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 21 May 2013 | 100 | 5,100 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 May 2013 | 600 | 37,909 | - | - | Common Stock, $0.001 par value | |
| Seth Lederman | Director, Chief Executive Officer, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 20 May 2013 | 400 | 38,309 | - | - | Common Stock, $0.001 par value | |
| Ernest Mario | None | 26 Apr 2013 | 166,667 | 216,667 | - | - | Warrants | ||
| Ernest Mario | None | 26 Apr 2013 | 166,667 | 1,447,079 | - | - | Common Stock | ||
| John B. Rhodes | None | 26 Apr 2013 | 166,667 | 1,268,603 | - | - | Common Stock | ||
| John B. Rhodes | None | 26 Apr 2013 | 166,667 | 383,333 | - | - | Warrants | ||
| Samuel R. Saks | None | 26 Apr 2013 | 166,667 | 333,334 | - | - | Common Stock | ||
| Samuel R. Saks | None | 26 Apr 2013 | 166,667 | 166,667 | - | - | Warrants | ||
| Stuart Davidson | None | 26 Apr 2013 | 166,667 | 1,490,716 | - | - | Common Stock | ||
| Stuart Davidson | None | 26 Apr 2013 | 166,667 | 216,667 | - | - | Warrants | ||
| Charles Mather | None | 26 Apr 2013 | 25,000 | 85,000 | - | - | Warrants | ||
| Charles Mather | None | 26 Apr 2013 | 25,000 | 175,569 | - | - | Common Stock | ||
| Leland Gershell | CFO and Treasurer | 26 Apr 2013 | 37,500 | 100,000 | - | - | Common Stock | ||
| Leland Gershell | CFO and Treasurer | 26 Apr 2013 | 37,500 | 62,500 | - | - | Warrants | ||
| Bruce Daugherty | See Remarks | 26 Apr 2013 | 37,500 | 204,167 | - | - | Common Stock | ||
| Bruce Daugherty | See Remarks | 26 Apr 2013 | 37,500 | 295,834 | - | - | Warrants | ||
| Ernest Mario | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 210,000 | 0 | - | - | Stock Option | |
| Patrick P. Grace | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 240,000 | 0 | - | - | Stock Option | |
| John B. Rhodes | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 225,000 | 0 | - | - | Stock Option | |
| Samuel R. Saks | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 210,000 | 0 | - | - | Stock Option | |
| Seth Lederman | Director, Chief Executive Officer, Ten Percent Owner | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 1,350,000 | 0 | - | - | Stock Option | |
| Stuart Davidson | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 225,000 | 0 | - | - | Stock Option | |
| Donald W. Landry | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 210,000 | 0 | - | - | Stock Option | |
| Charles Mather | None | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 210,000 | 0 | - | - | Stock Option | |
| Leland Gershell | CFO and Treasurer | Grant, award, or other acquisition of securities at price $ 0.00 per share. | 12 Feb 2013 | 1,050,000 | 0 | - | - | Stock Option | |
| David J. Moss | Director, PRES, CEO, TRES, CFO, SECR, Ten Percent Owner | Purchase of securities on an exchange or from another person at price $ 0.00 per share. | 05 May 2011 | 250,000 | 3,250,000 | - | - | Common shares |